Cas No.: 146998-31-4
PRODUCT INFORMATION
Description
Synonyms: 4-[4-(Dimethylamino)phenylazo]benzoic Acid N-Succinimidyl Ester / N-Succinimidyl 4-[4-(Dimethylamino)phenylazo]benzoate / DABCYL N-Succinimidyl Ester. This is an amine-reactive, non-fluorescent "dark quencher." The NHS ester labels primary amines. DABCYL absorbs broadly in the blue-green region (max ~475 nm) and dissipates the energy as heat instead of light. It is most commonly paired with a fluorophore (e.g., FAM, EDANS) to create "turn-off" probes. When a protease cleaves the linker between the dye and DABCYL, fluorescence is "turned on," making it ideal for enzyme assays.
Molecular Weight
366.38
Purity
>98.0%
Formula
C₁₉H₁₈N₄O₄
Product Type
Acceptors and Donors for FRET
Ex
543 nm
Em
578 nm
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, 0-10°C
Molecular Structure
For Research Use Only | Not For Clinical Use
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