Cas No.: 42014-51-7
PRODUCT INFORMATION
Description
This heterobifunctional crosslinker contains an amine-reactive N-hydroxysuccinimide (NHS) ester and a sulfhydryl-reactive bromoacetyl group. The NHS ester reacts with primary amines (lysines) at pH 7.0-9.0. The bromoacetyl group is a thiol-specific alkylating agent, reacting at pH 7.5-8.5 to form a highly stable, non-cleavable thioether bond. Compared to a maleimide, the bromoacetyl group is more stable to hydrolysis but generally reacts more slowly. It is used for short-range, stable crosslinking of amines to thiols.
Molecular Weight
236.02
Purity
>98.0%
Formula
C₆H₆BrNO₄
Product Type
Heterobifunctional Crosslinkers
Group 1
X (F, Cl, Br, I)
Group 2
NHS
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, <0°C
Molecular Structure
For Research Use Only | Not For Clinical Use
Related products
- t-Boc-N-amido-PEG4-acid PEGylation Crosslinker (CAT#: OLY-1023-YS116)
- Disuccinimidyl Suberate (DSS) Homobifunctional Crosslinker (CAT#: OLY-1023-YS132)
- 4-[3-(Trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid (TDBA) Photo-reactive Crosslinker (CAT#: OLY-1023-YS33)
- Hydroxy-PEG3-t-butyl Ester (CAT#: OLY-1023-YS42)
- [4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenyl]methanamine Hydrochloride Heterobifunctional Crosslinker (CAT#: OLY-1023-YS82)
- Hydroxy-PEG2-(CH2)2-Boc Heterobifunctional Crosslinker (CAT#: OLY-1023-YS51)
- Z-6-Aminohexanoic Acid Heterobifunctional Crosslinker (CAT#: OLY-1023-YS3)
- Mono-tert-butyl Succinate Homobifunctional Crosslinker (CAT#: OLY-1023-YS138)
Online Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.