Amino-PEG3-acid tert-butyl Ester Heterobifunctional Crosslinker (CAT#: OLY-1023-YS97)

Description

This is a heterobifunctional, hydrophilic PEG building block. It features a free primary amine and a t-butyl (OtBu) ester-protected carboxylic acid, separated by a 3-unit PEG spacer. The primary amine is available for immediate conjugation (e.g., to an NHS ester). The t-butyl ester provides robust, acid-labile protection for the carboxylic acid. This allows for selective deprotection using acid (e.g., TFA) to reveal the free carboxyl for a subsequent, orthogonal coupling step (e.g., via EDC/NHS activation). It is ideal for multi-step, sequential syntheses.

Molecular Weight

277.36

Purity

>90.0%

Formula

C₁₃H₂₇NO₅

Product Type

Heterobifunctional Crosslinkers

Group 1

NH₂

Group 2

Other

Form (20 deg.C)

Liquid

Storage Condition

Store under inert gas, -20°C

Molecular Structure