[4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenyl]methanamine Hydrochloride Heterobifunctional Crosslinker (CAT#: OLY-1023-YS82)

Description

This heterobifunctional linker is a key reagent for bioorthogonal 'Click Chemistry.' It features two distinct reactive groups: a primary amine (as an HCl salt for solubility) and a methyl-tetrazine. The tetrazine moiety is highly reactive towards strained alkenes, such as trans-cyclooctene (TCO) or bicyclononyne (BCN), via the extremely fast and bioorthogonal Inverse-Electron-Demand Diels-Alder (IEDDA) reaction. The primary amine allows for the easy conjugation of this tetrazine "handle" to biomolecules or surfaces, typically by reacting it with an activated carboxylic acid (e.g., an NHS ester).

Molecular Weight

237.69

Purity

>95.0%

Formula

C₁₀H₁₁N₅·HCl

Product Type

Heterobifunctional Crosslinkers

Group 1

Other

Group 2

Other

Form (20 deg.C)

Solid

Storage Condition

Store under inert gas, -20°C

Molecular Structure