Bioconjugation

t-Boc-N-amido-PEG4-acid PEGylation Crosslinker (CAT#: OLY-1023-YS116)

Datasheet MSDS

Cas No.: 756525-91-4

PRODUCT INFORMATION

Description
This is a heterobifunctional, hydrophilic PEGylation linker, a shorter analogue of the PEG6 version. It features a terminal carboxylic acid and an acid-labile Boc-protected amine, separated by a 4-unit PEG spacer. The carboxylic acid can be activated (e.g., with EDC/NHS) to couple with primary amines. The Boc group provides orthogonal, acid-labile protection, allowing the amine to be deprotected in a subsequent step using TFA. This linker is ideal for multi-step conjugations where a hydrophilic spacer and orthogonal (acid vs. base/neutral) reactivity are required.
Molecular Weight
365.42
Purity
>98.0%
Formula
C₁₆H₃₁NO₈
Product Type
Heterobifunctional Crosslinkers ; PEGylation Reagents
Group 1
COOH
Group 2
Other
Form (20 deg.C)
Liquid
Storage Condition
Store under inert gas, -20°C
Molecular Structure
For Research Use Only | Not For Clinical Use

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