m-PEG12-NHS Ester PEGylation Crosslinker (CAT#: OLY-1023-YS253)

Description

This is a monofunctional, amine-reactive PEGylation reagent with a long spacer. It features a 12-unit polyethylene glycol (PEG) chain, capped with an inert methoxy (m) group and functionalized with an N-hydroxysuccinimide (NHS) ester. The NHS ester targets primary amines. Its primary use is "PEGylation," the process of attaching a long, flexible, and hydrophilic polymer shield to a biomolecule. This is a common strategy in drug development to enhance the pharmacokinetic profile (e.g., increase half-life, stability) of therapeutic proteins or peptides.

Molecular Weight

685.76

Formula

C₃₀H₅₅NO₁₆

Product Type

PEGylation Reagents

Group 1

NHS

Form (20 deg.C)

Solid

Storage Condition

Store under inert gas, <0°C

Molecular Structure