Home > Products > Ad Fiber Knob & CD40 > Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (F(ab')2-scFv2)

Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (F(ab')2-scFv2)  (CAT#: BABFV-002)

Recombinant Anti-Ad fiber knob x Anti-CD40 Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-Ad fiber knob specificity is fused to the C terminus of the anti-CD40 Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing.
Datasheet INQUIRY

Specifications

Targets
Ad Fiber Knob & CD40
Type
Fab-Fc Fusion Proteins
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Acute myeloid leukaemic (AML)

Targets

Target 1
Ad Fiber Knob
Alternative Names
Ad fiber knob; Adenovirus fiber knob; adenovirus fiber protein; knob domain of Ad fiber
Target 2
CD40
Gene ID
UniProt ID
Alternative Names
CD40; CD40 molecule; p50; Bp50; CDW40; TNFRSF5
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
Online Inquiry

Related products of "Ad Fiber Knob & CD40"
See other bsAb targets related to "Ad Fiber Knob"

See other bsAb targets related to "CD40"

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Anti-Ad Fiber Knob x Anti-CD40 Bispecific Antibody (F(ab')2-scFv2) (BABFV-002). Click the button below to contact us or submit your feedback about this product.