Home > Products > CD2 & MUC1 > Recombinant Anti-CD2 x Anti-MUC1 Bispecific Antibody (scFv-IgG)

Recombinant Anti-CD2 x Anti-MUC1 Bispecific Antibody (scFv-IgG)  (BSSG-047)

Recombinant Anti-CD2 x Anti-MUC1 Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-CD2 antibody variable domain are respectively connected to the N terminus of the anti-MUC1 IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can retarget T cells to tumor cells. It is designed for the research of Breast cancer; Bile duct cancer (BDC) therapy.

Specifications
Targets
CD2 & MUC1
Type
Appended IgGs
Species Reactivity
Human
Target 1
CD2
Host Animal 1
Mouse
Target 2
MUC1
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Breast cancer; Bile duct cancer (BDC)
Targets
Target 1
CD2
Gene ID
UniProt ID
Alternative Names
CD2; CD2 molecule; T11; SRBC; LFA-2; T-cell surface antigen CD2; leukocyte function-associated antigen-2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor
Target 2
MUC1
Gene ID
UniProt ID
Alternative Names
MUC1; mucin 1, cell surface associated; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; mucin-1; episialin; DF3 antigen; H23 antigen; cancer antigen 15-3; krebs von den Lungen-6; mucin 1, transmembrane; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; Medullary cystic kidney disease, autosomal dominant
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