Name: Recombinant Anti-M2 x Anti-TCR (Vβ8) Bispecific Antibody (Fab-scFv-Fc)
SKU: FABVC-180
Rating: 5 (1 reviews)

Recombinant Anti-M2 x Anti-TCR (Vβ8) Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-M2 antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-TCR (Vβ8) to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can retarget T cells to virus-infected cells. It is designed for the research of Inﬂuenza virus infection therapy.

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Specifications

Targets

M2 & TCR (Vβ8)

Type

Fab-scFv/sdAb-Fc

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Inﬂuenza virus infection

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

Gene ID

956528

UniProt ID

P03428

Alternative Names

influenza virus M2 protein;M2

Target 2

TCR (Vβ8)

Gene ID

28588

Alternative Names

Trbv8; T cell receptor beta variable 8; TCR; T-cell receptor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-M2 x Anti-TCR (Vβ8) Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-180)

Specifications

Targets

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