Flower-derived Exosome Research and Applications

Flower-derived exosomes are extracellular vesicles that are isolated from various parts of flowers, such as petals, pollen, and leaves. Flower-derived exosomes have gained interest in research and applications due to their potential therapeutic and cosmetic benefits. Creative Biolabs has a specialized exosome research platform to advance the study of flower-derived exosomes and their potential.

Summary of Flower-derived Exosome Functions

  • Flower-derived exosomes exhibit antioxidant, anti-inflammatory, and rejuvenating properties for skin care and anti-aging.
  • The potential of flower-derived exosomes as carriers for targeted drug delivery has also been demonstrated.
  • Flower-derived exosomes are naturally capable of crossing biological barriers and are biocompatible, making them attractive candidates for delivering therapeutic agents to specific tissues or organs.
  • Flower-derived exosomes have shown promise in agricultural applications. They can enhance plant stress tolerance, promote growth, and aid in the protection against pathogens.

Strategies used for plant-derived nanovesicle loading. (Tinnirello, et al., 2023)Fig. 1 Strategies used for plant-derived nanovesicle loading.1

Advances in Flower-derived Exosome

Flower-derived exosome types Research case
Catharanthus roseus-derived Exosome Catharanthus roseus-derived exosomes attenuated cyclophosphamide-induced immunosuppressive effects and up-regulated the hematopoietic-related transcription factor PU.1 after intraperitoneal injection into mice, showing potential for the treatment of immune system disorders.
Aloe-derived Exosome Aloe vera-derived exosomes detect active ingredients such as aloesin, aloe-emodin, and β-sitosterol, as well as glucose ceramides as their main lipid type, which are antioxidant and pro-repairing.
Rose-derived Exosome Exosomes isolated from roses have great potential to be powerful cosmetics that promote skin regeneration, increase skin suppleness, and minimize wrinkles.
Centella-derived Exosome Centella asiatica-derived exosomes carry asiaticoside that activates epithelial cells and promotes the formation of normal granulation tissue, which contributes to wound healing. Also, they prevent disorderly keloid proliferation and post-traumatic tissue adhesion by inhibiting the proliferation of fibroblasts.
Tea Flower-derived Exosome Tea flower-derived vesicles contain a variety of active substances such as catechins, flavonoids, functional proteins, and lipids. Findings suggest that they can modulate intestinal flora and inhibit metastatic breast cancer in tumor-bearing mice after intravenous or oral administration.
Tea-derived Exosome Naturally occurring exosome-like vesicles in fresh tea exhibit excellent breast cancer therapeutic potential, and their oral administration avoids adverse effects such as hepatotoxicity and abnormal activation of the immune system.
Honey-derived Exosome Honey-derived exosomes present in honey whose nectar has been transformed by converting enzymes from the hypopharyngeal glands of worker bees show antimicrobial effects.

It is worth noting that research on flower-derived exosomes is still in its early stages and further investigation is needed to fully understand their functions and potential applications. Creative Biolabs is delighted to support projects related to these with exosome development and discovery services. Please contact us to describe your needs.

Reference

  1. Tinnirello, Vincenza, et al. "Exploiting the Opportunity to Use Plant-Derived Nanoparticles as Delivery Vehicles." Plants 12.6 (2023): 1207.
For Research Use Only. Cannot be used by patients.
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