This product is a Farage B cell engineering tool based on the Gold nanoparticles (SS-Fc/Carcinoembryonic antigen) delivery system and CRISPR-based (CCR5-tracr RNA-Cas9-Brefeldin A) genome editor.
| Host Cell | Farage |
| Target | EGFR |
| Insert Clone | BG-23A |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | Brefeldin A |
| Targeting Strategy | pH responsive |
| Insertion sites | Mouse genome E-2 |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | SS-Fc/Carcinoembryonic antigen |
| Active Agents | AntimiR-21, doxorubicin (DOX) |
| Particle Size | <100 |
| Charge (mv) | 0 to -16 |
| Total Atom Count | -22000000 |
| Surface Atoms (%) | -3 |
| Specific Surface Area (m2/g) | -9 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Pancreatic cancer; Ovarian cancer; Breast cancer; Colon cancer |
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