This product is a Raji B cell engineering tool based on the Nanoparticles (Mannose/Mannose receptor) delivery system and CRISPR-based (CCR5-SpCas9-NLS-Cas9-RS-1) genome editor.
| Host Cell | Raji |
| Target | EGFR |
| Insert Clone | BG-25A |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | SpCas9 |
| Nuclease | NLS-Cas9 |
| Enhancer | RS-1 |
| Targeting Strategy | pH-dependent |
| Insertion sites | Large DNA sequences |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | DOX |
| Particle Size | 10-1000 |
| Charge (mv) | -25 to -125 |
| Total Atom Count | -22000000 |
| Surface Atoms (%) | -3 |
| Specific Surface Area (m2/g) | -9 |
| Vector Type | VSV |
| Vector Name | BCpCDH7 |
| Targeting Diseases | Pancreatic cancer; Ovarian cancer; Breast cancer; Colon cancer |
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