This product is a Raji-Luc2 B cell engineering tool based on the Solid lipid nanoparticles (SS-Fc/Carcinoembryonic antigen) delivery system and CRISPR-based (huROSA-26-tracr RNA-Cas9-SCR7 pyrazine) genome editor.
| Host Cell | Raji-Luc2 |
| Target | EGFR |
| Insert Clone | BG-33A |
| Safe Harbor Sites (SHS) | huROSA-26 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | SCR7 pyrazine |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Human genome |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | SS-Fc/Carcinoembryonic antigen |
| Active Agents | 5-Fluorouracil (5-FU) |
| Particle Size | <1000 |
| Charge (mv) | 10-93 |
| Total Atom Count | -57000000 |
| Surface Atoms (%) | -0.8 |
| Specific Surface Area (m2/g) | -2.5 |
| Vector Type | MSCV |
| Vector Name | BCpCDH6 |
| Targeting Diseases | Pancreatic cancer; Ovarian cancer; Breast cancer; Colon cancer |
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