This product is a Raji-Luc2 B cell engineering tool based on the Solid lipid nanoparticles (AS1411 aptamer/Nucleolin) delivery system and CRISPR-based (hROSA26-tracr RNA-Cas9-SCR7 pyrazine) genome editor.
| Host Cell | Raji-Luc2 |
| Target | EphA2 |
| Insert Clone | 1C7CR |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | SCR7 pyrazine |
| Targeting Strategy | pH responsive |
| Insertion sites | Large DNA sequences |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | AS1411 aptamer/Nucleolin |
| Active Agents | [Ru(bpy)2(tip)]2+, RBT |
| Particle Size | 10-1000 |
| Charge (mv) | -1 to -20 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Adenoviruses |
| Vector Name | BCpCDH3 |
| Targeting Diseases | Colon cancer; Lung cancer; Brain cancer; Renal cancer; Leukemia |
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