This product is a Ramos (RA 1) B cell engineering tool based on the Quantum dots (Folate/ Folate Receptor) delivery system and CRISPR-based (CCR5-crispr RNA-SpCas9-RS-1) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | EphA2 |
| Insert Clone | B6CR64 |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | pH responsive |
| Insertion sites | Large DNA sequences |
| Vehicles | Quantum dots |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | 5-Fluorouracil (5-FU) |
| Particle Size | 20-2850 |
| Charge (mv) | 10 to 55 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | Adenoviruses |
| Vector Name | BCpCDH3 |
| Targeting Diseases | Colon cancer; Lung cancer; Brain cancer; Renal cancer; Leukemia |
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