This product is a Raji-Luc2 B cell engineering tool based on the Niosomes (Folate/ Folate Receptor) delivery system and CRISPR-based (hROSA26-crispr RNA-SpCas9-RS-1) genome editor.
| Host Cell | Raji-Luc2 |
| Target | EphA2 |
| Insert Clone | B6CR76 |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | pH responsive |
| Insertion sites | Mouse genome E-7 |
| Vehicles | Niosomes |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | DOX |
| Particle Size | 20-150 |
| Charge (mv) | 10 to 100 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Colon cancer; Lung cancer; Brain cancer; Renal cancer; Leukemia |
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