This product is a RPMI 1788 B cell engineering tool based on the Solid lipid nanoparticles (Transferrin/Transferrin receptor) delivery system and CRISPR-based (hROSA26-huIgH296-Cpf1-RS-1) genome editor.
| Host Cell | RPMI 1788 |
| Target | EZR |
| Insert Clone | BCGR-0267CR |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | huIgH296 |
| Nuclease | Cpf1 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | pH-dependent |
| Insertion sites | Large DNA sequences |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Transferrin/Transferrin receptor |
| Active Agents | Regorafenib |
| Particle Size | <500 |
| Charge (mv) | <-1 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | VSV |
| Vector Name | BCpCDH7 |
| Targeting Diseases | Breast cancer; Colon cancer; Lung cancer; Ovarian cancer |
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