EZR mAb (BCGR-1442CR) U266B1 [U266] B Cell Engineering Cassette (CAT#: BGS-0424-CR556)

This product is a U266B1 [U266] B cell engineering tool based on the Solid lipid nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (AAVS1-crispr RNA-SpCas9-3'-Azido-3'-deoxythymidine) genome editor.

Datasheet

Specifications

Host Cell U266B1 [U266]
Target EZR
Insert Clone BCGR-1442CR
Safe Harbor Sites (SHS) AAVS1
gRNA crispr RNA
Nuclease SpCas9
Enhancer 3'-Azido-3'-deoxythymidine
Targeting Strategy pH responsive, time-dependent
Insertion sites Human genome
Vehicles Solid lipid nanoparticles
Ligand/Receptor Folate/ Folate Receptor
Active Agents 5-Fluorouracil (5-FU)
Particle Size 10-500
Charge (mv) 0 to -30
Total Atom Count -33000000
Surface Atoms (%) -3.5
Specific Surface Area (m2/g) -5.5
Vector Type Lentivirus
Vector Name BCpCDH2
Targeting Diseases Breast cancer; Colon cancer; Lung cancer; Ovarian cancer
COA

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