This product is a ST486 B cell engineering tool based on the Nanoparticles (N-acetyl-D-glucosamine, sialic acid/Wheat germ agglutinin) delivery system and CRISPR-based (SHS-227-tracr RNA-Cas9-Nocodazole) genome editor.
| Host Cell | ST486 |
| Target | FAP |
| Insert Clone | BCG-2568CR |
| Safe Harbor Sites (SHS) | SHS-227 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | Nocodazole |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Mouse genome E-8 |
| Vehicles | Nanoparticles |
| Ligand/Receptor | N-acetyl-D-glucosamine, sialic acid/Wheat germ agglutinin |
| Active Agents | Celastrol |
| Particle Size | <1660 |
| Charge (mv) | <-1 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | RABV |
| Vector Name | BCpCDH8 |
| Targeting Diseases | Ovarian cancer; Breast cancer; Colon cancer |
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