This product is a Raji-Luc2 B cell engineering tool based on the Solid lipid nanoparticles (Folate/ Folate Receptor) delivery system and CRISPR-based (CCR5-huIgH296-Cas9-SCR7 pyrazine) genome editor.
| Host Cell | Raji-Luc2 |
| Target | MIF |
| Insert Clone | RAM4C |
| Safe Harbor Sites (SHS) | CCR5 |
| gRNA | huIgH296 |
| Nuclease | Cas9 |
| Enhancer | SCR7 pyrazine |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Large DNA sequences |
| Vehicles | Solid lipid nanoparticles |
| Ligand/Receptor | Folate/ Folate Receptor |
| Active Agents | Talazoparib, temozolomide |
| Particle Size | 22-2410 |
| Charge (mv) | −7 to -77 |
| Total Atom Count | -23000000 |
| Surface Atoms (%) | -4 |
| Specific Surface Area (m2/g) | -7 |
| Vector Type | Baculovirus-AAV |
| Vector Name | BCpCDH4 |
| Targeting Diseases | Lung cancer; Brain cancer; Colon cancer; Ovarian cancer; Liver cancer |
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