This product is a P3HR-1 B cell engineering tool based on the Nanoparticles (MUC1 aptamer/MUC1) delivery system and CRISPR-based (SHS-229-crispr RNA-SpCas9-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | P3HR-1 |
| Target | MIF |
| Insert Clone | RAMQ |
| Safe Harbor Sites (SHS) | SHS-229 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | Enzyme responsive, time-dependent |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Nanoparticles |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | DOX |
| Particle Size | <241 |
| Charge (mv) | 11-91 |
| Total Atom Count | -23000000 |
| Surface Atoms (%) | -4 |
| Specific Surface Area (m2/g) | -7 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Lung cancer; Brain cancer; Colon cancer; Ovarian cancer; Liver cancer |
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