This product is a Raji-Luc2 B cell engineering tool based on the Gold nanoparticles (MUC1 aptamer/MUC1) delivery system and CRISPR-based (SHS-323-crRNA:tracrRNA duplex-Cas12-SCR7 pyrazine) genome editor.
| Host Cell | Raji-Luc2 |
| Target | NAB2 |
| Insert Clone | 1B10-CR |
| Safe Harbor Sites (SHS) | SHS-323 |
| gRNA | crRNA:tracrRNA duplex |
| Nuclease | Cas12 |
| Enhancer | SCR7 pyrazine |
| Targeting Strategy | pH responsive |
| Insertion sites | Nonhomologous target sites |
| Vehicles | Gold nanoparticles |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | Talazoparib, temozolomide |
| Particle Size | <500 |
| Charge (mv) | 13 to 65 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | Baculovirus-AAV |
| Vector Name | BCpCDH4 |
| Targeting Diseases | Lung canccer; Ovarian cancer; Liver cancer |
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