This product is a Ramos (RA 1) B cell engineering tool based on the Sphingosomes (Hyaluronic acid/ RHAMM, CD44) delivery system and CRISPR-based (hROSA26-SpCas9-NLS-Cas9-Brefeldin A) genome editor.
| Host Cell | Ramos (RA 1) |
| Target | NAB2 |
| Insert Clone | 3H5CR |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | SpCas9 |
| Nuclease | NLS-Cas9 |
| Enhancer | Brefeldin A |
| Targeting Strategy | pH responsive |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Sphingosomes |
| Ligand/Receptor | Hyaluronic acid/ RHAMM, CD44 |
| Active Agents | 5-Fluorouracil (5-FU) |
| Particle Size | 20-2850 |
| Charge (mv) | ≤50 |
| Total Atom Count | -70000000 |
| Surface Atoms (%) | -0.8 |
| Specific Surface Area (m2/g) | -2.5 |
| Vector Type | RABV |
| Vector Name | BCpCDH8 |
| Targeting Diseases | Lung canccer; Ovarian cancer; Liver cancer |
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.