This product is a SU-DHL-5 B cell engineering tool based on the Nanoparticles (SS-Fc/Carcinoembryonic antigen) delivery system and CRISPR-based (AAVS1-crispr RNA-SpCas9-RS-1) genome editor.
| Host Cell | SU-DHL-5 |
| Target | NAB2 |
| Insert Clone | 1C4-CR |
| Safe Harbor Sites (SHS) | AAVS1 |
| gRNA | crispr RNA |
| Nuclease | SpCas9 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | Enzyme responsive, time-dependent |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Nanoparticles |
| Ligand/Receptor | SS-Fc/Carcinoembryonic antigen |
| Active Agents | Thymoquinone |
| Particle Size | <100 |
| Charge (mv) | <-1 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | MMLV |
| Vector Name | BCpCDH5 |
| Targeting Diseases | Lung canccer; Ovarian cancer; Liver cancer |
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