This product is a SU-DHL-10 B cell engineering tool based on the Nanoparticles (Mannose/Mannose receptor) delivery system and CRISPR-based (SHS-317-sgRNA-Cpf1-3'-Azido-3'-deoxythymidine) genome editor.
| Host Cell | SU-DHL-10 |
| Target | NAB2 |
| Insert Clone | 1H3-CR |
| Safe Harbor Sites (SHS) | SHS-317 |
| gRNA | sgRNA |
| Nuclease | Cpf1 |
| Enhancer | 3'-Azido-3'-deoxythymidine |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Nanoparticles |
| Ligand/Receptor | Mannose/Mannose receptor |
| Active Agents | Bortezomib |
| Particle Size | 20-2850 |
| Charge (mv) | 10 to 35 |
| Total Atom Count | -70000000 |
| Surface Atoms (%) | -0.8 |
| Specific Surface Area (m2/g) | -2.5 |
| Vector Type | Lentivirus |
| Vector Name | BCpCDH2 |
| Targeting Diseases | Lung canccer; Ovarian cancer; Liver cancer |
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