This product is a Raji B cell engineering tool based on the Nanoparticles (MUC1 aptamer/MUC1) delivery system and CRISPR-based (SHS-317-tracr RNA-Cas9-RS-1) genome editor.
| Host Cell | Raji |
| Target | NEUROG3 |
| Insert Clone | 4B2-CR |
| Safe Harbor Sites (SHS) | SHS-317 |
| gRNA | tracr RNA |
| Nuclease | Cas9 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | pH responsive, mucoadhesiveness |
| Insertion sites | Mouse genome E-3 |
| Vehicles | Nanoparticles |
| Ligand/Receptor | MUC1 aptamer/MUC1 |
| Active Agents | Bortezomib |
| Particle Size | 10-1000 |
| Charge (mv) | 10 to 55 |
| Total Atom Count | -75000000 |
| Surface Atoms (%) | -0.65 |
| Specific Surface Area (m2/g) | -0.7 |
| Vector Type | MMLV |
| Vector Name | BCpCDH5 |
| Targeting Diseases | Lung cancer; Breast cancer; Prostate cancer; Melanoma |
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