3-N-Maleimidobenzoic Acid-NHS (MBS) Heterobifunctional Crosslinker (CAT#: OLY-1023-YS106)
Datasheet MSDSCas No.: 58626-38-3
PRODUCT INFORMATION
Description
MBS is a non-cleavable, heterobifunctional crosslinker. It features an amine-reactive N-hydroxysuccinimide (NHS) ester and a sulfhydryl-reactive maleimide group. The NHS ester reacts with primary amines (lysines) at pH 7.0-9.0. The maleimide group targets thiols (cysteines) at pH 6.5-7.5. These two groups are separated by a short, rigid aromatic (benzoic acid) spacer. This rigidity provides a defined, short-range linkage. MBS is widely used to conjugate proteins to peptides, and its hydrophobic nature makes it membrane-permeable for intracellular crosslinking.
Molecular Weight
314.25
Purity
>98.0%
Formula
C₁₅H₁₀N₂O₆
Product Type
Heterobifunctional Crosslinkers
Group 1
Maleimide
Group 2
NHS
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, 2-8°C
Molecular Structure
For Research Use Only | Not For Clinical Use
Related products
- 6-Maleimido-hexanoic NHS (EMCS) Heterobifunctional Crosslinker (CAT#: OLY-1023-YS109)
- N-Succinimidyl Bromoacetate Heterobifunctional Crosslinker (CAT#: OLY-1023-YS28)
- 4-Maleimidobutyric Acid Heterobifunctional Crosslinker (CAT#: OLY-1023-YS10)
- Boc-Lys(Myr)-OH Albumin Binding Conjugation Reagent (CAT#: OLY-1023-YS173)
- Biotin-PEG2-hydrazide Biotins Conjugation Reagent (CAT#: OLY-1023-YS208)
- Boc-NH-C6-NHS (CAT#: OLY-1023-YS1)
- Dithiobis(succinimidyl propionate) (DSP) Homobifunctional Crosslinker (CAT#: OLY-1023-YS141)
- Biotin Hydrazide Biotins Conjugation Reagent (CAT#: OLY-1023-YS184)
Online Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.