3-N-Maleimidobenzoic Acid-NHS (MBS) Heterobifunctional Crosslinker (CAT#: OLY-1023-YS106)
Datasheet MSDSCas No.: 58626-38-3
PRODUCT INFORMATION
Description
MBS is a non-cleavable, heterobifunctional crosslinker. It features an amine-reactive N-hydroxysuccinimide (NHS) ester and a sulfhydryl-reactive maleimide group. The NHS ester reacts with primary amines (lysines) at pH 7.0-9.0. The maleimide group targets thiols (cysteines) at pH 6.5-7.5. These two groups are separated by a short, rigid aromatic (benzoic acid) spacer. This rigidity provides a defined, short-range linkage. MBS is widely used to conjugate proteins to peptides, and its hydrophobic nature makes it membrane-permeable for intracellular crosslinking.
Molecular Weight
314.25
Purity
>98.0%
Formula
C₁₅H₁₀N₂O₆
Product Type
Heterobifunctional Crosslinkers
Group 1
Maleimide
Group 2
NHS
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, 2-8°C
Molecular Structure
For Research Use Only | Not For Clinical Use
Related products
- N-(2-Aminoethyl)maleimide Hydrochloride Heterobifunctional Crosslinker (CAT#: OLY-1023-YS90)
- Biotin-PEG3-azide Biotins Conjugation Reagent (CAT#: OLY-1023-YS196)
- m-PEG24-maleimide PEGylation Crosslinker (CAT#: OLY-1023-YS246)
- 6-Biotinamidohexanoic Acid (CAT#: OLY-1023-YS190)
- Dibenzocyclooctyne-S-S-PEG3-biotin Copper-Free Click Chemistry Reagent (CAT#: OLY-1023-YS211)
- Maleimide-PEG4-NHS Ester PEGylation Crosslinker (CAT#: OLY-1023-YS233)
- Amino-PEG6-acid PEGylation Crosslinker (CAT#: OLY-1023-YS63)
- N-([ε-Maleimidocaproyloxy)sulfosuccinimide Ester (Sulfo-EMCS) (CAT#: OLY-1023-YS88)
Online Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.