Cas No.: 1422540-88-2
PRODUCT INFORMATION
Description
This is a heterobifunctional, hydrophilic linker for 'Click Chemistry' and thiol-based conjugations. It contains: 1) A terminal alkyne group for Copper(I)-catalyzed (CuAAC) click reactions with azides. 2) An S-acetyl-protected thiol group. This thioester is stable to click conditions but can be selectively cleaved with a mild base (e.g., hydroxylamine) to reveal a free sulfhydryl group. This free thiol can then be used for a subsequent conjugation, such as reacting with a maleimide or immobilizing onto a gold surface. The 4-unit PEG spacer adds hydrophilicity.
Molecular Weight
290.37
Purity
>98.0%
Formula
C₁₃H₂₂O₅S
Product Type
Heterobifunctional Crosslinkers
Group 1
Alkyne
Group 2
Other
Form (20 deg.C)
Liquid
Storage Condition
Store under inert gas, -20°C
Molecular Structure
For Research Use Only | Not For Clinical Use
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