Cas No.: 1263045-16-4
PRODUCT INFORMATION
Description
This is a heterobifunctional, hydrophilic PEGylation crosslinker. It features a sulfhydryl-reactive maleimide group and a terminal carboxylic acid, separated by a 4-unit PEG spacer. The maleimide group reacts specifically with thiols (e.g., cysteine residues) at pH 6.5-7.5 to form a stable thioether bond. The carboxylic acid can be activated (e.g., with EDC/NHS) to react with primary amines (e.g., lysine residues). This linker is ideal for conjugating thiol-containing molecules to amine-containing molecules (or vice-versa), with the PEG4 spacer enhancing solubility.
Molecular Weight
416.43
Purity
>95.0%
Formula
C₁₈H₂₈N₂O₉
Product Type
Heterobifunctional Crosslinkers ; PEGylation Reagents
Group 1
Maleimide
Group 2
COOH
Form (20 deg.C)
Solid
Storage Condition
2-8°C
Molecular Structure
For Research Use Only | Not For Clinical Use
Related products
- t-Boc-N-amido-PEG4-acid PEGylation Crosslinker (CAT#: OLY-1023-YS116)
- Amino-PEG3-acid tert-butyl Ester Heterobifunctional Crosslinker (CAT#: OLY-1023-YS97)
- N-(2-Aminoethyl)maleimide Hydrochloride Heterobifunctional Crosslinker (CAT#: OLY-1023-YS90)
- Palm-Glu(OSu)-OtBu Albumin Binding Conjugation Reagent (CAT#: OLY-1023-YS178)
- Azide-PEG3-desthiobiotin (CAT#: OLY-1023-YS206)
- Mono-tert-butyl Succinate Homobifunctional Crosslinker (CAT#: OLY-1023-YS138)
- Amino-PEG4-Boc (CAT#: OLY-1023-YS71)
- Tris(2-carboxyethyl)phosphine Hydrochloride (TCEP) (CAT#: OLY-1023-YS302)
Online Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.