Cas No.: 1263045-16-4
PRODUCT INFORMATION
Description
This is a heterobifunctional, hydrophilic PEGylation crosslinker. It features a sulfhydryl-reactive maleimide group and a terminal carboxylic acid, separated by a 4-unit PEG spacer. The maleimide group reacts specifically with thiols (e.g., cysteine residues) at pH 6.5-7.5 to form a stable thioether bond. The carboxylic acid can be activated (e.g., with EDC/NHS) to react with primary amines (e.g., lysine residues). This linker is ideal for conjugating thiol-containing molecules to amine-containing molecules (or vice-versa), with the PEG4 spacer enhancing solubility.
Molecular Weight
416.43
Purity
>95.0%
Formula
C₁₈H₂₈N₂O₉
Product Type
Heterobifunctional Crosslinkers ; PEGylation Reagents
Group 1
Maleimide
Group 2
COOH
Form (20 deg.C)
Solid
Storage Condition
2-8°C
Molecular Structure
For Research Use Only | Not For Clinical Use
Related products
- Dithiodiglycolic Acid (CAT#: OLY-1023-YS153)
- Fmoc-N-amido-PEG12-acid PEGylation Crosslinker (CAT#: OLY-1023-YS75)
- Mc-Val-Cit-PABC-PNP Enzyme Cleavable Linker for ADC (CAT#: OLY-1023-YS270)
- Mono-tert-butyl Succinate Homobifunctional Crosslinker (CAT#: OLY-1023-YS138)
- Streptavidin from Streptomyces Avidinii (CAT#: OLY-1023-YS215)
- 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium Chloride (CAT#: OLY-1023-YS292)
- N,N'-Ethylenedimaleimide (CAT#: OLY-1023-YS137)
- 3-Azidopropylamine Heterobifunctional Crosslinker (CAT#: OLY-1023-YS64)
Online Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.