Cas No.: 1263045-16-4
PRODUCT INFORMATION
Description
This is a heterobifunctional, hydrophilic PEGylation crosslinker. It features a sulfhydryl-reactive maleimide group and a terminal carboxylic acid, separated by a 4-unit PEG spacer. The maleimide group reacts specifically with thiols (e.g., cysteine residues) at pH 6.5-7.5 to form a stable thioether bond. The carboxylic acid can be activated (e.g., with EDC/NHS) to react with primary amines (e.g., lysine residues). This linker is ideal for conjugating thiol-containing molecules to amine-containing molecules (or vice-versa), with the PEG4 spacer enhancing solubility.
Molecular Weight
416.43
Purity
>95.0%
Formula
C₁₈H₂₈N₂O₉
Product Type
Heterobifunctional Crosslinkers ; PEGylation Reagents
Group 1
Maleimide
Group 2
COOH
Form (20 deg.C)
Solid
Storage Condition
2-8°C
Molecular Structure
For Research Use Only | Not For Clinical Use
Related products
- Alloc-Val-Cit-PAB-OH Enzyme Cleavable Linker for ADC (CAT#: OLY-1023-YS271)
- m-PEG4-NHS Ester PEGylation Crosslinker (CAT#: OLY-1023-YS251)
- Fmoc-N-amido-PEG12-acid PEGylation Crosslinker (CAT#: OLY-1023-YS75)
- PEG Dithiol 5000 (CAT#: OLY-1023-YS262)
- Biotin-HPDP Biotins Conjugation Reagent (CAT#: OLY-1023-YS218)
- 3-N-Maleimidobenzoic Acid-NHS (MBS) Heterobifunctional Crosslinker (CAT#: OLY-1023-YS106)
- PEG Diamine 2000 (CAT#: OLY-1023-YS259)
- 4-Maleimidobutyric Acid NHS (GMBS) Heterobifunctional Crosslinker (CAT#: OLY-1023-YS107)
Online Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.