Cas No.: 1137109-21-7
PRODUCT INFORMATION
Description
This is a heterobifunctional, hydrophilic PEGylation crosslinker. It features a sulfhydryl-reactive maleimide group and an amine-reactive N-hydroxysuccinimide (NHS) ester, separated by a 6-unit polyethylene glycol (PEG) spacer. The NHS ester reacts efficiently with primary amines (pH 7.0-9.0), while the maleimide targets thiols (pH 6.5-7.5). The hydrophilic PEG6 spacer significantly enhances aqueous solubility, reduces aggregation, and provides a flexible, long-distance linkage. This linker is ideal for covalently linking proteins to peptides, haptens, or surfaces in a simple, two-step procedure.
Molecular Weight
601.61
Purity
>98.0%
Formula
C₂₆H₃₉N₃O₁₃
Product Type
Heterobifunctional Crosslinkers ; PEGylation Reagents
Group 1
Maleimide
Group 2
NHS
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, -20°C
Molecular Structure
For Research Use Only | Not For Clinical Use
Related products
- Hydroxy-PEG3-t-butyl Ester (CAT#: OLY-1023-YS42)
- Disuccinimidyl Suberate (DSS) Homobifunctional Crosslinker (CAT#: OLY-1023-YS132)
- Di(N-succinimidyl) Pimelate Homobifunctional Crosslinker (CAT#: OLY-1023-YS136)
- β-Alanine tert-butyl Ester Hydrochloride Heterobifunctional Crosslinker (CAT#: OLY-1023-YS112)
- SPDP NHS Ester Heterobifunctional Crosslinker (CAT#: OLY-1023-YS27)
- m-PEG4-NHS Ester PEGylation Crosslinker (CAT#: OLY-1023-YS251)
- Alloc-Val-Cit-PAB-OH Enzyme Cleavable Linker for ADC (CAT#: OLY-1023-YS271)
- N-Succinimidyl Methacrylate Heterobifunctional Crosslinker (CAT#: OLY-1023-YS25)
Online Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.