m-PEG4-NHS Ester PEGylation Crosslinker (CAT#: OLY-1023-YS251)

Description

This is a monofunctional, amine-reactive PEGylation reagent. It features a 4-unit polyethylene glycol (PEG) chain capped at one end with an inert methoxy (m) group and functionalized at the other with an N-hydroxysuccinimide (NHS) ester. The NHS ester reacts efficiently with primary amines (lysines) at pH 7.0-9.0. This reagent is used to attach a short, hydrophilic, and biochemically inert PEG tail to proteins, peptides, or small molecules to improve aqueous solubility, modify spacing, or reduce non-specific binding.

Molecular Weight

333.34

Formula

C₁₄H₂₃NO₈

Product Type

PEGylation Reagents

Group 1

NHS

Form (20 deg.C)

Liquid

Storage Condition

Store under inert gas, <0°C

Molecular Structure