Cas No.: 57078-98-5
PRODUCT INFORMATION
Description
This is a non-cleavable, heterobifunctional crosslinker featuring a sulfhydryl-reactive maleimide group and a terminal carboxylic acid, separated by a short 4-carbon (C4) aliphatic spacer. The maleimide group reacts specifically with thiols (cysteine residues) at pH 6.5-7.5. The carboxylic acid can be activated (e.g., with EDC/NHS) to react with primary amines (lysine residues). This linker is used to covalently connect amine-containing molecules to thiol-containing molecules over a short, defined distance, making it useful for creating stable bioconjugates or for surface functionalization.
Molecular Weight
183.16
Purity
>98.0%
Formula
C₈H₉NO₄
Product Type
Heterobifunctional Crosslinkers
Group 1
Maleimide
Group 2
COOH
Form (20 deg.C)
Solid
Storage Condition
2-8°C
Molecular Structure
For Research Use Only | Not For Clinical Use
Related products
- (R)-α-Lipoic Acid Heterobifunctional Crosslinker (CAT#: OLY-1023-YS8)
- N,N'-Disuccinimidyl Carbonate (CAT#: OLY-1023-YS131)
- Propargyl Ether Homobifunctional Crosslinker (CAT#: OLY-1023-YS139)
- Bis-PEG9-NHS Ester PEGylation Crosslinker (CAT#: OLY-1023-YS168)
- Amino-PEG3-amine PEGylation Crosslinker (CAT#: OLY-1023-YS147)
- 3-Maleimido-propionic NHS (BMPS) Heterobifunctional Crosslinker (CAT#: OLY-1023-YS108)
- N-Succinimidyl 4-(4-Maleimidophenyl)butyrate (SMPB) Heterobifunctional Crosslinker (CAT#: OLY-1023-YS53)
- Amino-PEG6-acid PEGylation Crosslinker (CAT#: OLY-1023-YS63)
Online Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.