Cas No.: 57078-98-5
PRODUCT INFORMATION
Description
This is a non-cleavable, heterobifunctional crosslinker featuring a sulfhydryl-reactive maleimide group and a terminal carboxylic acid, separated by a short 4-carbon (C4) aliphatic spacer. The maleimide group reacts specifically with thiols (cysteine residues) at pH 6.5-7.5. The carboxylic acid can be activated (e.g., with EDC/NHS) to react with primary amines (lysine residues). This linker is used to covalently connect amine-containing molecules to thiol-containing molecules over a short, defined distance, making it useful for creating stable bioconjugates or for surface functionalization.
Molecular Weight
183.16
Purity
>98.0%
Formula
C₈H₉NO₄
Product Type
Heterobifunctional Crosslinkers
Group 1
Maleimide
Group 2
COOH
Form (20 deg.C)
Solid
Storage Condition
2-8°C
Molecular Structure
For Research Use Only | Not For Clinical Use
Related products
- [4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenyl]methanamine Hydrochloride Heterobifunctional Crosslinker (CAT#: OLY-1023-YS82)
- N-Succinimidyl Bromoacetate Heterobifunctional Crosslinker (CAT#: OLY-1023-YS28)
- Biotin-PEG4-hydrazide Biotins Conjugation Reagent (CAT#: OLY-1023-YS205)
- Fmoc-N-amido-PEG6-acid PEGylation Crosslinker (CAT#: OLY-1023-YS6)
- 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium Chloride (CAT#: OLY-1023-YS292)
- 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide (CAT#: OLY-1023-YS284)
- Mal-amido-PEG2-NHS (CAT#: OLY-1023-YS14)
- N-Succinimidyl 4-Benzoylbenzoate Photo-reactive Crosslinker (CAT#: OLY-1023-YS30)
Online Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.