Bioconjugation

Mono-tert-butyl Succinate Homobifunctional Crosslinker (CAT#: OLY-1023-YS138)

Datasheet MSDS

Cas No.: 15026-17-2

PRODUCT INFORMATION

Description
This is a heterobifunctional building block, not a direct crosslinker. It is a derivative of succinic acid with two distinct ends: 1) A free carboxylic acid, which can be activated (e.g., with EDC/NHS) to couple with primary amines. 2) A t-butyl (OtBu) ester-protected carboxylic acid. The t-butyl ester provides robust, acid-labile protection. This allows for selective deprotection using acid (e.g., TFA) after the first coupling, revealing a new carboxyl group. It is used to introduce a short, functional "handle" in multi-step syntheses.
Molecular Weight
174.20
Purity
>98.0%
Formula
C₈H₁₄O₄
Product Type
Homobifunctional Crosslinkers
Group 1
COOH
Group 2
COOH
Form (20 deg.C)
Solid
Storage Condition
2-8°C
Molecular Structure
For Research Use Only | Not For Clinical Use

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