Bioconjugation

Dibenzocyclooctyne-S-S-PEG3-biotin Copper-Free Click Chemistry Reagent (CAT#: OLY-1023-YS211)

Datasheet MSDS

Cas No.: 1430408-09-5

PRODUCT INFORMATION

Description
This is a trifunctional, cleavable biotinylation reagent for copper-free 'Click Chemistry.' It features: 1) A DBCO (dibenzocyclooctyne) group for rapid, strain-promoted (SPAAC) reaction with azides. 2) A biotin tag for detection or purification. 3) A central disulfide (S-S) bond. The PEG3 spacer enhances solubility. This reagent is used to label azide-functionalized molecules. The key feature is that the biotin tag can be cleaved off the labeled molecule under mild reducing conditions (e.g., DTT, TCEP), enabling gentle elution from streptavidin affinity columns.
Molecular Weight
869.12
Purity
>90.0%
Formula
C₄₂H₅₆N₆O₈S₃
Product Type
Biotins and Streptavidins ; Copper-Free Click Chemistry Reagents
Group 1
Biotin
Group 2
Other
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, -20°C
Molecular Structure
For Research Use Only | Not For Clinical Use

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