Dibenzocyclooctyne-S-S-PEG3-biotin Copper-Free Click Chemistry Reagent (CAT#: OLY-1023-YS211)

Description

This is a trifunctional, cleavable biotinylation reagent for copper-free 'Click Chemistry.' It features: 1) A DBCO (dibenzocyclooctyne) group for rapid, strain-promoted (SPAAC) reaction with azides. 2) A biotin tag for detection or purification. 3) A central disulfide (S-S) bond. The PEG3 spacer enhances solubility. This reagent is used to label azide-functionalized molecules. The key feature is that the biotin tag can be cleaved off the labeled molecule under mild reducing conditions (e.g., DTT, TCEP), enabling gentle elution from streptavidin affinity columns.

Molecular Weight

869.12

Purity

>90.0%

Formula

C₄₂H₅₆N₆O₈S₃

Product Type

Biotins and Streptavidins ; Copper-Free Click Chemistry Reagents

Group 1

Biotin

Group 2

Other

Form (20 deg.C)

Solid

Storage Condition

Store under inert gas, -20°C

Molecular Structure