N-Succinimidyl 7-Hydroxycoumarin-3-carboxylate Fluorescent Label (CAT#: OLY-1123-LD41)
Datasheet MSDSCas No.: 134471-24-2
PRODUCT INFORMATION
Description
Synonyms: 7-Hydroxycoumarin-3-carboxylic Acid N-Succinimidyl Ester / N-Succinimidyl Umbelliferone-3-carboxylate / Umbelliferone-3-carboxylic Acid N-Succinimidyl Ester. This is the activated, amine-reactive (NHS ester) form of 7-hydroxycoumarin. It reacts directly with primary amines (lysines) at pH 7.0-9.0 to form stable, blue-fluorescent conjugates. Because the 7-hydroxy group remains free, the fluorescence of the resulting conjugate is pH-sensitive (pKa ~7.8). This makes it useful for creating labeled biomolecules that can act as ratiometric probes for local pH changes.
Molecular Weight
303.23
Purity
>96.0%
Formula
C₁₄H₉NO₇
Product Type
Fluorescent Labels ; Acceptors and Donors for FRET
Ex
360 nm
Em
410 nm
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, <0°C
Molecular Structure
For Research Use Only | Not For Clinical Use
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