Cas No.: 882847-13-4
PRODUCT INFORMATION
Description
This is a heterobifunctional, hydrophilic PEGylation linker. It features a terminal carboxylic acid and an acid-labile Boc (tert-Butyloxycarbonyl)-protected amine, separated by a 6-unit PEG spacer. The carboxylic acid can be activated (e.g., with EDC/NHS) to couple with primary amines. The Boc group provides robust, orthogonal protection. It is stable to the neutral/basic conditions of carboxyl activation but can be selectively removed with mild acid (e.g., TFA) to expose the free amine for a subsequent conjugation step. The PEG6 spacer adds hydrophilicity and flexibility.
Molecular Weight
453.53
Purity
>98.0%
Formula
C₂₀H₃₉NO₁₀
Product Type
Heterobifunctional Crosslinkers ; PEGylation Reagents
Group 1
COOH
Group 2
Other
Form (20 deg.C)
Liquid
Storage Condition
Store under inert gas, -20°C
Molecular Structure
For Research Use Only | Not For Clinical Use
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