t-Boc-N-amido-PEG6-acid PEGylation Crosslinker (CAT#: OLY-1023-YS115)

Description

This is a heterobifunctional, hydrophilic PEGylation linker. It features a terminal carboxylic acid and an acid-labile Boc (tert-Butyloxycarbonyl)-protected amine, separated by a 6-unit PEG spacer. The carboxylic acid can be activated (e.g., with EDC/NHS) to couple with primary amines. The Boc group provides robust, orthogonal protection. It is stable to the neutral/basic conditions of carboxyl activation but can be selectively removed with mild acid (e.g., TFA) to expose the free amine for a subsequent conjugation step. The PEG6 spacer adds hydrophilicity and flexibility.

Molecular Weight

453.53

Purity

>98.0%

Formula

C₂₀H₃₉NO₁₀

Product Type

Heterobifunctional Crosslinkers ; PEGylation Reagents

Group 1

COOH

Group 2

Other

Form (20 deg.C)

Liquid

Storage Condition

Store under inert gas, -20°C

Molecular Structure