Bioconjugation

N-Hydroxysulfosuccinimide Sodium Salt (Sulfo-NHS) Zero-Length Crosslinker (CAT#: OLY-1023-YS288)

Datasheet MSDS

Cas No.: 106627-54-7

PRODUCT INFORMATION

Description
Sulfo-NHS is not a crosslinker on its own but an additive used with carbodiimides like EDC. EDC activates carboxyl groups, and Sulfo-NHS rapidly reacts with this intermediate to form a stable, water-soluble Sulfo-NHS ester. This amine-reactive ester has a longer half-life than the EDC intermediate, significantly improving the efficiency of coupling to primary amines. It is ideal for labeling proteins in aqueous buffers while minimizing side reactions.
Molecular Weight
217.13
Purity
>98.0%
Formula
C₄H₄NNaO₆S
Product Type
Zero-Length Crosslinkers ; Functional Group Creating Reagents
Group 1
NHS
Form (20 deg.C)
Solid
Storage Condition
Store under inert gas, 2-8°C
Molecular Structure
For Research Use Only | Not For Clinical Use

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