Home > Products > B cell lymphoma 38C13 Idiotype & LFA-1 > Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Diabody-Fc)

Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Diabody-Fc)  (BSDBF-014)

Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-B cell lymphoma 38C13 Idiotype and anti-LFA-1 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can block cell adhesion. It is designed for the research of B cell lymphoma therapy.

Specifications

Targets
B cell lymphoma 38C13 Idiotype & LFA-1
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Mouse
Target 1
B cell lymphoma 38C13 Idiotype
Host Animal 1
Rat
Target 2
LFA-1
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
B cell lymphoma

Targets

Target 1
B cell lymphoma 38C13 Idiotype
Alternative Names
B cell lymphoma 38C13 Idiotype; B cell lymphoma; 38C13; Idiotype; Id
Target 2
LFA-1
Gene ID
UniProt ID
Alternative Names
integrin subunit alpha L; Integrin beta chain-2; ITGB2; Integrin subunit beta 2; MF17, MAC-1; ITGAL; CD11A; LFA-1; LFA1A; ITGAL; CD18; LCAMB; AI528527; 2E6; LAD

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