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B Cell Lymphoma 38C13 Idiotype & LFA-1 Bispecific Antibodies
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CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Tandem Diabody) Mouse Tandem Diabody B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
SCIGG-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scIgG) Mouse Single chain IgGs B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
FVTIG-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scFv4-Ig) Mouse scFv4-Ig B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSSG-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scFv-IgG) Mouse scFv-IgG B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
IGLFV-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (IgG(L)-scFv) Mouse IgG-scFv B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSGV-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (IgG-Fv) Mouse IgG-Fv B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSDG-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fv-IgG) Mouse Fv-IgG B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BABFV-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (F(ab')2-scFv2) Mouse F(ab')2-scFv2 B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
FABVC-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fab-scFv-Fc) Mouse Fab-scFv/sdAb-Fc B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
SCDBC-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scDiabody-CH3) Mouse scDiabody-CH3 B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSDBC-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Diabody-CH3) Mouse Diabody-CH3 B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
SCDBF-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scDiabody-Fc) Mouse scDiabody-Fc B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSFVF-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Tandem scFv-Fc) Mouse Tandem scFv-Fc B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSDBF-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Diabody-Fc) Mouse Diabody-Fc B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSTF-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scFv-Fc-scFv) Mouse scFv-Fc-scFv B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSCFV-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scFv-Fc) Mouse scFv-Fc B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
MNAB-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Miniantibody) Mouse Miniantibody B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSFC-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scFv-CH3) Mouse scFv-CH3 B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSCC-014 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (scFv-CH1/CL) Mouse scFv-CH1/CL B cell lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BIBD-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Bibody) Mouse Bibody B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
FABFV-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fab-Fv) Mouse Fab-Fv B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
MiniB-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Minibody) Mouse Minibody B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
SCDB-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Single-chain Diabody) Mouse Single-chain Diabody B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
FABIG-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fab-IgG) Mouse Fab-IgG B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
TRIB-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fab-scFv-scFv) Mouse Fab-scFv-scFv B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSIG-014 Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (IgG-IgG) Mouse IgG-IgG B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
CROSSAB-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (CrossMab) Mouse CrossMab B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
IGFV-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (IgG-scFv) Mouse IgG-scFv B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSDB-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Diabody) Mouse Diabody B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSFAB-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Tandem Fab) Mouse Tandem Fab B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
BSFV-014 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Tandem scFv) Mouse Tandem scFv B Cell Lymphoma 38C13 Idiotype Rat LFA-1 Mouse Inquiry
T-BSDB-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Tandem Diabody) Mouse Tandem Diabody B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
SCIGG-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (scIgG) Mouse Single chain IgGs B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
FVTIG-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (scFv4-Ig) Mouse scFv4-Ig B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSSG-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (scFv-IgG) Mouse scFv-IgG B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
IGLFV-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (IgG(L)-scFv) Mouse IgG-scFv B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSGV-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (IgG-Fv) Mouse IgG-Fv B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSDG-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Fv-IgG) Mouse Fv-IgG B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BABFV-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (F(ab')2-scFv2) Mouse F(ab')2-scFv2 B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
FABVC-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Fab-scFv-Fc) Mouse Fab-scFv/sdAb-Fc B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
SCDBC-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (scDiabody-CH3) Mouse scDiabody-CH3 B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSDBC-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Diabody-CH3) Mouse Diabody-CH3 B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
SCDBF-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (scDiabody-Fc) Mouse scDiabody-Fc B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSFVF-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Tandem scFv-Fc) Mouse Tandem scFv-Fc B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSDBF-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Diabody-Fc) Mouse Diabody-Fc B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSTF-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (scFv-Fc-scFv) Mouse scFv-Fc-scFv B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSCFV-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (scFv-Fc) Mouse scFv-Fc B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
MNAB-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Miniantibody) Mouse Miniantibody B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSFC-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (scFv-CH3) Mouse scFv-CH3 B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSCC-013 Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (scFv-CH1/CL) Mouse scFv-CH1/CL B cell lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BIBD-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Bibody) Mouse Bibody B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
FABFV-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Fab-Fv) Mouse Fab-Fv B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
MiniB-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Minibody) Mouse Minibody B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
SCDB-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Single-chain Diabody) Mouse Single-chain Diabody B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
FABIG-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Fab-IgG) Mouse Fab-IgG B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
TRIB-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Fab-scFv-scFv) Mouse Fab-scFv-scFv B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSIG-013 Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (IgG-IgG) Mouse IgG-IgG B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
CROSSAB-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (CrossMab) Mouse CrossMab B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
IGFV-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (IgG-scFv) Mouse IgG-scFv B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSDB-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Diabody) Mouse Diabody B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSFAB-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Tandem Fab) Mouse Tandem Fab B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry
BSFV-013 Recombinant Anti-B Cell Lymphoma 38C13 Idiotype x Anti-CD44 Bispecific Antibody (Tandem scFv) Mouse Tandem scFv B Cell Lymphoma 38C13 Idiotype Rat CD44 Rat Inquiry

Background

The mature tumor-specific antigen, B cell lymphoma 38C13 idiotype, serves as a crucial marker for in vivo immune response. Integrin beta 2, also known as LFA-1, functions as a cell membrane-located adhesion factor, playing a role in tumor cell migration and mediating interactions with the extracellular matrix and surrounding cells. Recent research has demonstrated that anti-adhesion molecular antibodies can prevent lymphoma metastasis and deterioration. Therefore, a bispecific antibody targeting the adhesion molecule LFA-1 and the tumor-specific antigen 38C13 idiotype has been designed by Creative Biolabs for B cell lymphoma therapy research, aiming to block tumor metastasis while preserving normal interactions.

B cell lymphoma idiotype and LFA-1 structure. (López-Requena, et al., 2012; Kondo, et al., 2022) Fig.1 B cell lymphoma idiotype and LFA-1 structure. Left: B cell lymphoma idiotype; Right: LFA-1.1, 2

References

  1. López-Requena, Alejandro, Oscar R. Burrone, and Michela Cesco-Gaspere. "Idiotypes as immunogens: facing the challenge of inducing strong therapeutic immune responses against the variable region of immunoglobulins." Frontiers in Oncology 2 (2012): 159.
  2. Kondo, Naoyuki, Yoshihiro Ueda, and Tatsuo Kinashi. "LFA1 activation: Insights from a single-molecule approach." Cells 11.11 (2022): 1751.
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