Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fab-scFv-Fc) (FABVC-014)

Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fab-scFv-Fc) requires expression of three polypeptide chains, encoding two heavy chains (Fc-containing chains) and one light chain, respectively. The Fab of anti-B cell lymphoma 38C13 Idiotype antibody variable domain is fused to the Fc-knob domain with a hinge region and the same as the scFv of anti-LFA-1 to the Fc-hole domain, or vice versa. The Fab-Fc and scFv-Fc fragments can be paired via the interaction of the Fc regions. This BsAb can block cell adhesion. It is designed for the research of B cell lymphoma therapy.

Datasheet INQUIRY

Specifications

Targets

B cell lymphoma 38C13 Idiotype & LFA-1

Type

Fab-Fc Fusion Proteins

Species Reactivity

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

B cell lymphoma

Targets

Target 1

B cell lymphoma 38C13 Idiotype

Alternative Names

B cell lymphoma 38C13 Idiotype; B cell lymphoma; 38C13; Idiotype; Id

Target 2

LFA-1

Gene ID

16414

UniProt ID

P24063

Alternative Names

integrin subunit alpha L; Integrin beta chain-2; ITGB2; Integrin subunit beta 2; MF17, MAC-1; ITGAL; CD11A; LFA-1; LFA1A; ITGAL; CD18; LCAMB; AI528527; 2E6; LAD

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-B cell lymphoma 38C13 Idiotype x Anti-LFA-1 Bispecific Antibody (Fab-scFv-Fc) (CAT#: FABVC-014)

Specifications

Targets

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