Recombinant Human Anti-CD32B x Human Anti-malaria antigen Bispecific Antibody (scFv-CH3) (BSFC-H289)

Recombinant Anti-CD32B x Anti-malaria antigen Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD32B scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-malaria antigen scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can retarget NK cells to genus plasmodium. It is designed for the research of Malaria therapy.

Datasheet INQUIRY

Specifications

Targets

CD32B & malaria antigen

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Malaria

Targets

Target 1

CD32B

Gene ID

2213

UniProt ID

P31994

Alternative Names

FCGR2B; Fc fragment of IgG, low affinity IIb, receptor (CD32); FcγRIIB; CD32; FCG2; CD32B; FCGR2; IGFR2; low affinity immunoglobulin gamma Fc region receptor II-b; CDw32; fcRII-b; Fc gamma RIIb; fc-gamma-RIIb; fc-gamma RII-b; igG Fc receptor II-b; Fc fragment of IgG, low affinity II, receptor for (CD32); Fc fragment of IgG, low affinity IIb, receptor for (CD32)

Target 2

malaria antigen

Alternative Names

malaria antigen; parasitic protozoans

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD32B x Human Anti-malaria antigen Bispecific Antibody (scFv-CH3) (CAT#: BSFC-H289)

Specifications

Targets

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