Home > Products > CEA & nido-carboranes > Recombinant Anti-CEA x Anti-nido-carboranes Bispecific Antibody (Bibody)

Recombinant Anti-CEA x Anti-nido-carboranes Bispecific Antibody (Bibody)  (BIBD-141)

Recombinant Anti-CEA x Anti-nido-carboranes Bispecific Antibody (Bibody) is a Fab-scFv format that uses heterodimeric Fab as a scaffold, and a scFv region linked to one of its heavy (Fd) or light (L) chain. The scFv of the anti-CEA specificity is fused to the anti-nido-carboranes heavy or light chain of the Fab. This BsAb can be used in pretargeting system of PET, radioimaging or radiotherapy. It can mediate targeting of radioactivity to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer imaging and therapy.

Specifications

Targets
CEA & nido-carboranes
Type
Bibody
Species Reactivity
Human
Target 1
CEA
Host Animal 1
Mouse
Target 2
nido-carboranes
Host Animal 2
Mouse
Application
FuncS; Pretargeting system for radioimaging and radiotherapy
Related Disease
Breast cancer; Ovary cancer; Colon cancer; Lung cancer

Targets

Target 1
CEA
Gene ID
UniProt ID
Alternative Names
CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
nido-carboranes
Alternative Names
nido-carboranes

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