Recombinant Anti-CSF1 x Anti-IL34 Bispecific Antibody (Diabody-CH3) (BSDBC-143)

Recombinant Anti-CSF1 x Anti-IL34 Bispecific Antibody (Diabody-CH3) is a fusion protein of two diabodies connected together by a CH3 region. In a diabody, the two scFvs with short linkers are from anti-CSF1 and anti-IL34 antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to each of the CH3 chains, which results in 2+2 antigen-binding valency and extends the half-life of this BsAb. This BsAb can bind two factors simultaneously. It is designed for the research of Myeloid pathogenic immunological diseases therapy.

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Specifications

Targets

CSF1 & IL34

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Myeloid pathogenic immunological diseases

Targets

Target 1

CSF1

Gene ID

1435

UniProt ID

A0A024R0A1

Alternative Names

CSF1; colony stimulating factor 1 (macrophage); MCSF; CSF-1; macrophage colony-stimulating factor 1; lanimostim

Target 2

IL34

Gene ID

146433

UniProt ID

Q6ZMJ4

Alternative Names

IL-34; C16orf77; interleukin 34

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CSF1 x Anti-IL34 Bispecific Antibody (Diabody-CH3) (CAT#: BSDBC-143)

Specifications

Targets

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