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Recombinant Anti-CSF1 x Anti-IL34 Bispecific Antibody (scFv4-Ig)  (CAT#: FVTIG-143)

Recombinant Anti-CSF1 x Anti-IL34 Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-CSF1 scFv is fused to the CH1 domain of a heavy chain and another anti-IL34 scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can bind two factors simultaneously. It is designed for the research of Myeloid pathogenic immunological diseases therapy.
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Specifications

Targets
CSF1 & IL34
Type
Appended IgGs
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Myeloid pathogenic immunological diseases

Targets

Target 1
CSF1
Gene ID
UniProt ID
Alternative Names
CSF1; colony stimulating factor 1 (macrophage); MCSF; CSF-1; macrophage colony-stimulating factor 1; lanimostim
Target 2
IL34
Gene ID
UniProt ID
Alternative Names
IL-34; C16orf77; interleukin 34
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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