Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (scFv-CH3) (BSFC-172)

Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (scFv-CH3) contains two chains. The anti-IL13 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-IL17 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Asthma therapy.

Datasheet INQUIRY

Specifications

Targets

IL13 & IL17

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Asthma

Targets

Target 1

IL13

Gene ID

3596

UniProt ID

P35225

Alternative Names

IL13; interleukin 13; P600; IL-13; interleukin-13

Target 2

IL17

Gene ID

3605

UniProt ID

Q16552

Alternative Names

IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-IL13 x Anti-IL17 Bispecific Antibody (scFv-CH3) (CAT#: BSFC-172)

Specifications

Targets

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