Name: Recombinant Human Anti-Nkp46 x Mouse Anti-BCMA Bispecific Antibody (Tandem Fab)
SKU: KN-0725-N77
Rating: 5 (1 reviews)

Recombinant Human Anti-Nkp46 x Mouse Anti-BCMA Bispecific Antibody (Tandem Fab) is designed to be expressed as three chains derived from the variable domains of anti-Nkp46 and anti-BCMA parental antibodies. It contains a His-tag for affinity purification. And the two Fd regions are connected by a flexible linker. This BsAb can retarget NK cells to tumor cells. It is designed for the research of Multiple myeloma (MM) therapy.

Datasheet INQUIRY

Specifications

Targets

Nkp46 & BCMA

Type

Tandem Fab

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Multiple myeloma (MM)

Host Animal 1

Human

Host Animal 2

Mouse

Targets

Target 1

Nkp46

Gene ID

9437

UniProt ID

O76036

Alternative Names

CD335; NCR1; Natural Cytotoxicity Triggering Receptor 1, gene symbol; NK-p46; Natural Killer Cell Activating Receptor p46; LY94; CD335; NKP46; NK-p46; Natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NCR1

Target 2

BCMA

Gene ID

608

UniProt ID

Q02223

Alternative Names

TNFRSF17; tumor necrosis factor receptor superfamily, member 17; BCM; BCMA; CD269; TNFRSF13A; tumor necrosis factor receptor superfamily member 17; B-cell maturation factor; B cell maturation antigen; B-cell maturation protein

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-Nkp46 x Mouse Anti-BCMA Bispecific Antibody (Tandem Fab) (CAT#: KN-0725-N77)

Specifications

Targets

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