Recombinant Anti-pre S2 protein x Anti-S protein Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-pre S2 protein antibody are fused to the C terminus of an anti-S protein IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can bind two antigens simultaneously. It is designed for the research of HBV infection therapy.