Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsCreative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
Highlights| Protein Name | Glucagon like peptide 2 receptor |
| Gene Name | GLP2R |
| Uniprot | O95838 (Human); Q5IXF8 (Mouse) |
| Synonym | GLP-2 receptor; epididymis secretory sperm binding protein |
| Background | The glucagon-like peptide 2 receptor (GLP2R) is a receptor protein encoded by the gene GLP2R. The G protein activates adenylate cyclase to mediate the activity of the GLP2R receptor. GLP2 signaling can stimulate intestinal growth and increase the villus height in the small intestine, accompanied by an increase in crypt cell proliferation and a decrease in intestinal cell apoptosis. |
Creative Biolabs offers comprehensive range of membrane protein products empowers your unique research needs.
| CAT# | Product Name | Expression System | Protein Length | Solubilizing Agents |
| S01YF-1023-KX382 | NativeExtract™ Human GLP2R Membrane Protein (Full length, Super Nanodisc) | HEK293 cells | Full length | Native Nanodisc |
| MPX3630K | MemDX™ Membrane Protein Human GLP2R (Glucagon like peptide 2 receptor) Expressed in vitro E.coli expression system, Full Length | E.colicell-free | Full length | Detergent |
| Please for more products or customization | ||||
C***y: The customer support team was also fantastic. They were very responsive and provided helpful information to ensure I got the best results. I highly recommend Creative Biolabs to anyone in need of high-quality proteins.
17/ Aug/2023
D***ta: I had a few questions before placing the order, and the customer service team was very knowledgeable and helpful. They provided detailed answers and even some additional tips for using the protein.
03/ Oct/2023
We provide tailored solutions to meet your specific requirements. Please for more services.
Creative Biolabs offers vector design and optimization services. Adeno-associated viral (AAV) vectors are a leading gene delivery system commonly employed in modern gene therapy research. Their notable advantages include a generally low immunogenicity, allowing them to evade the immune system's detection, and the ability to effectively transduce both non-dividing (quiescent) and actively dividing cell types. This versatility enables their wide-ranging use within living organisms. When using this vector system for gene therapy approaches focused on the GLP2R, careful design and construction of the vector are of utmost importance. The GLP2R coding sequence must be placed under the regulatory control of an appropriate promoter element. The choice of promoter profoundly influences the resultant expression pattern.
Creative Biolabs offers gene expression regulation services. To achieve targeted expression of the GLP2R gene in the gastrointestinal tract, tissue-specific promoters can be used. For example, the intestinal fatty acid binding protein (I-FABP) promoter can drive the expression of GLP2R specifically in the intestinal epithelial cells. This can help minimize off-target effects and reduce the risk of adverse events in other tissues.
Creative Biolabs offers comprehensive and innovative services to drive the development of GLP2R cell therapy. Please for more services.
Creative Biolabs offers receptor engineering services. Alter the GLP2R protein directly to boost its signaling efficacy and the binding affinity for GLP-2. Site-specific mutagenesis can be harnessed to introduce precise mutations into the receptor, thereby enhancing its activation process or the downstream signaling cascades.
Creative Biolabs offers chimeric receptor construction services. Generate chimeric receptors by integrating segments of GLP2R with other receptors that possess favorable characteristics. These chimeric receptors can be made to be expressed in target cells through genetic engineering methods.
Creative Biolabs offers inhibition of negative regulators research services. Enhancing GLP2R signaling entails the detection and subsequent functional suppression of endogenous inhibitory regulators functioning within its related pathways. The rationale behind this approach is to oppose the molecular processes that typically dampen GLP2R signal transmission, thus possibly elevating the overall strength and duration of the signaling. Particular methods used to attain this might involve the application of highly specific small-molecule blockers aimed at crucial negative regulatory proteins.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
