Creative Biolabs is offering the most comprehensive services for antibody development projects. With strict regulation and effective execution, we are dedicated to providing the most valuable solutions to complete your projects.
HighlightsWith over a decade of experience in phage display technology, Creative Biolabs can provide a series of antibody or peptide libraries that are available for licensing or direct screening. These ready-to-use libraries are invaluable resources for isolating target-specific binders for various research, diagnostic or therapeutic applications. Highlights
Creative Biolabs has established a broad range of platforms for developing novel antibodies or equivalents. These cutting-edge technologies enable our scientists to meet your demands from different aspects and tailor the most appropriate solution that contributes to the success of your projects.
HighlightsWith deep understanding in antibody-related realms and extensive project experience, Creative Biolabs offers a variety of references to help you learn more about our capacities and achievements, including infographic, flyer, case study, peer-reviewed publications, and all kinds of knowledge that can assist your projects. You are also welcome to contact us directly for more specific solutions.
HighlightsGet a real taste of Creative Biolabs, one of the most professional custom service providers in the world. We are committed to providing highly customized comprehensive solutions with the best quality to advance your projects.
HighlightsVoltage-gated potassium channels (VGKCs) are identified as transmembrane channels that are specific for potassium and sensitive to voltage changes in the cell's membrane potential and play a key role in setting the resting membrane potential. VGKCs are assembled from membrane-integrated alpha subunits and auxiliary beta subunits and are involved in a variety of functions, including secretion, electrogenesis, and cell motility. Voltage-gated potassium channel beta subunits are cytoplasmic proteins that co-purify with the pore-forming alpha subunits. Beta subunits are auxiliary proteins which associate with alpha subunits, sometimes in an alpha4beta4 stoichiometry. The potassium channel beta subunits are found in particular abundance in the central nervous system of mammals, and also expressed in invertebrates and plants.
Voltage-gated potassium channel beta subunits do not conduct current on their own but rather regulate the activity of Kv (potassium voltage-gated ion) channels. And they are suggested to be functionally important in human heart. Here, the two members of voltage-gated potassium channel beta subunit family are covered in further detail.
Based on our Magic™ membrane protein production platform, scientists at Creative Biolabs have devoted themselves in providing the protein preparation services of these membrane proteins mentioned above in required formats through different strategies, including detergent micelles, proteoliposomes, nanodiscs, lipoparticles, polymers, with stable cell line.
In addition, Magic™ membrane protein antibody discovery platform at Creative Biolabs can be utilized for developing antibodies against these targets, even fully humanized antibodies, by various approaches such as hybridoma technology, phage display technology, and etc. We also present DNA immunization service for anti-membrane protein antibody development. Please feel free to contact us for technical help.
All listed services and products are For Research Use Only. Do Not use in any diagnostic or therapeutic applications.
