This product is a SU-DHL-8 B cell engineering tool based on the Dendrimers (Fucoidan/P-selectin) delivery system and CRISPR-based (hROSA26-huIgH296-Cas9-RS-1) genome editor.
| Host Cell | SU-DHL-8 |
| Target | NEUROG2 |
| Insert Clone | 4B3CR |
| Safe Harbor Sites (SHS) | hROSA26 |
| gRNA | huIgH296 |
| Nuclease | Cas9 |
| Enhancer | RS-1 (RAD51-stimulatory compound 1) |
| Targeting Strategy | Enzyme responsive |
| Insertion sites | Unproductive heavy chain |
| Vehicles | Dendrimers |
| Ligand/Receptor | Fucoidan/P-selectin |
| Active Agents | 5-Fluorouracil (5-FU) |
| Particle Size | 20-2850 |
| Charge (mv) | -10 to -50 |
| Total Atom Count | -33000000 |
| Surface Atoms (%) | -3.5 |
| Specific Surface Area (m2/g) | -5.5 |
| Vector Type | RABV |
| Vector Name | BCpCDH8 |
| Targeting Diseases | Breast cancer; Lung cancer; Colorectal cancer |
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